ibuprofen beats naproxene


Regular intake of naproxen entails more CV risk than ibuprofen, according to an analysis of NSAID use among participants in the Women’s Health Initiative. Regular intake of ibuprofen, in fact, did not seem to involve any elevation in CV risk. The analysis, published July 8 in Circulation: Cardiovascular Quality and Outcomes, also saw a complicated relationship between aspirin and most other NSAIDs. It suggested that concomitant aspirin may alleviate the increased CV risk long associated with selective inhibitors of COX-2 such as celecoxib, but not the risk from others, such as naproxen.

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